I used Spyware Doctor some time back, I dont know if its the same program but it messed up a program called Spell Catcher because it classed it as a keylogger, I could not get it sorted even with suggestions from the company so uninstalled Spyware Doctor.

I use SyncbackSE and have not had any problems but as said by others it can depend on settings and how you use it.

My conclusion
 

Since I first disabled & then removed spyware doctor, this problem of lost data has not re-occurred.

I don't believe SyncBack was the culprit.

Last note: If user uses 'save as' to force a manual backup, change DB name because URp will automatically load that DB & you will know where you are. I couldn't tell because I stupidly didn't change names.

I don't like relying solely on software to save my work & I wish there was a simple manual save that was always available.