I've never used Outlook so I can't say whether UR can replace its functionalities cause I don't know what it offers ... all my tasks, appointments are in UR exclusivelly. Apart from the missing nice visual calendar view, I'm quite happy with it ...
and as you probably know, the tasks, appointments and searches can get quite sophisticated in UR, I doubt Outlook offers as much as UR when you do sth like GTD or similar ...
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